Simvastatin (Zocor) and 
Experience Responses Bmj
Five men with coronary artery disease developed impotence within one week of starting treatment with simvastatin 10 mg or having the dose increased to 20 mg (three men), they also had profound lethargy and inertia. Drug treatment for heart disease (aspirin alone in two patients) was not changed. Within one week of stopping simvastatin sexual function was restored.References 1↵ Scandinavian Simvastatin Study Group Randomised trial of cholesterol lowering in 4444 patients with coronary heart disease the Scandinavian Simvastatin Survival Study 4S Lancet 19943441383–9 2↵ Shepherd J Cobbe SM Ford I Isles CG Lorimer AR MacFarlane PW et al for the West of Scotland Coronary Prevention Study Group Prevention of coronary heart disease with pravastatin in men with hypercholesterolemia N Engl J Med 19953331301–7 3↵ Boyd IW Comment HMG CoA reductase inhibitor induced impotence Ann Pharmacother 1996301199
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