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Women in Study More Susceptible

Women in Study Review Experience Cancer Sfgate

A report in the Journal of the National Cancer Institute gives weight to an unproven theory that women may be more vulnerable than men to the cancer-causing substances in tobacco smoke.

The study found that female smokers with lung cancer were three times as likely as their male counterparts to have a damaged gene often found with a particularly lethal form of the disease Wiencke speculates that the female hormone estrogen already linked to breast and ovarian cancers may promote the growth of lung tissues containing genes damaged by tobacco smoke Breast cancer is still the most common cancer among women but since 1987 lung cancer has become the No 1 killer Since 1950 the mortality rate for lung cancer among women has risen 600 percent The study of 106 women lung cancer patients in Missouri found that those exposed to second hand smoke were 26 times as likely as other patients to carry a defective version of a gene that normally helps the body deactivate cancer causing chemicals Additionally women found to carry a damaged K ras gene might be suitable candidates for estrogen blocking therapy using drugs such as tamoxifen which are used to prevent a recurren


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